The Association for Retinopathy of 
Prematurity and Related Diseases

 August 27, 2008 

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ROPARD Online Education Section Module 2 

Module 2 – Peripheral Ablation

 Peripheral ablation for retinopathy of prematurity is based on the data from the Retinopathy of Prematurity Cryo Study.  The Retinopathy of Prematurity Cryo Study suggests the use of cryo ablation in the periphery.  With the advent of the laser indirect ophthalmoscope, cryotherapy is a less desirable mode of peripheral ablation.  In the situation where no other treatment is available, cryotherapy perhaps has a place, but where both therapies are available, laser ablation is much superior, as cryotherapy leads to an effusion following treatment that can be damaging to the retina.  Treatment with laser is best done with the red diode laser, although green argon laser can also be used.  The concern with the green laser is that absorption in and around the lens by the tunica vasculosa lentis may lead to cataract formation. 

 The treatment pattern for laser is important.  A near confluent treatment pattern yields the best result.  The photograph of the laser pattern in this module shows a laser pattern that is too widely spaced.  The laser spots should be placed approximately one-half of the laser spot dimension apart.  This pattern should be loosened however in the horizontal meridians to avoid anterior segment ischemia, which can have varying degrees following treatment ranging from cataract presentation to extreme hypotony and phthisis resulting after a period of this hypotony.  The child may need a second or sometimes even a third laser treatment.  These cases however are rare constituting probably fifteen percent at most of the eyes treated with peripheral ablation.

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